Macrocytosis is a common laboratory abnormality seen in various clinical settings. The reported prevalence across various studies range from 1.7-4 %^.4-9 Macrocytosis precedes anaemia and can occur without anaemia. Mild macrocytosis with Mean Corpuscular Volume (MCV) between 100-110 femtolitres(fl) is more common than severe macrocytosis and can remain unexplained even after extensive evaluation.⁸ Macrocytic anaemia is classified into two groups-Megaloblastic and nonmegaloblastic anaemia depending upon the morphological and biochemical finding. We conducted this study to find out the underlying aetiologies in patients with macrocytosis. We also evaluated various clinical, biochemical and haematological features in these patients so as to find out the difference between megaloblastic macrocytic and non-megaloblastic macrocytic anaemia. This has important clinical implications as assays of serum B₁₂ and folate levels may not be available in all the centres, especially in resource-poor settings and also these assays may not be accurate. Hence any finding of macrocytosis should be thoroughly evaluated as it can precede anaemia, or symptoms of underlying disease process, thereby helping in early diagnosis and treatment.

Leprosy is a chronic infectious disease of humans caused by Mycobacterium leprae. Leprosy is present in practically every corner of the globe, but in tropical countries like lndia, it is a major problem of public health importance. This problem can be tackled by correct diagnosis and timely treatment.

The clinical diagnosis of leprosy has to be confirmed by various diagnostic procedures e.g., histopathology, slit skin smears for Bacteriological Index (BI) and Morphological Index (Ml). These procedures are well established and accepted all over the world.

With the increasing role of cytology in the diagnosis of many diseases, few workers thought of employing the technique of Fine Needle Aspiration Cytology (FNAC) in leprosy cases and tried to find its correlation with histopathology.

Thus, the present study was undertaken to know the possible role of cytology in the diagnosis of leprosy, as it was felt that further documentation is required, due to paucity of similar studies.

Gilbert Syndrome is a rare benign condition of abnormal bilirubin conjugation. Patients with Gilbert syndrome are usually asymptomatic except for intermittent episode of unconjugated hyperbilirubinaemia, needing no treatment. We report a case of 14 year old boy with persistent hyperbilirubinaemia otherwise asymptomatic, diagnosed clinically as Gilbert syndrome.

We present the case of a young male admitted with Cushing's syndrome and a pituitary microadenoma for trans-sphenoidal surgery. An equivocal ACTH level and incomplete work up for the hypercortisolism prompted postponement of the surgery in favour of further investigation which revealed an adrenal adenoma. He finally underwent a laparoscopic left adrenalectomy which proved curative.