Moza 5 mg
Moza is used to treat severe reflux oesophagitis (also known as gastroesophageal reflux disease or GORD), where all other treatments have failed or cannot be tolerated. Moza is also used to treat gastroparesis or delayed emptying of the stomach, which causes food to stay longer in the stomach before passing into the intestine due to impaired muscle contractions and this can cause several unpleasant symptoms, including, vomiting, nausea, heartburn and dyspepsia.
Moza help restore the natural rhythm of muscle contraction and relaxation in the stomach to relieve gastrointestinal symptoms like heartburn and dyspepsia (indigestion and abdominal pain), caused by the acidic contents of the stomach flowing back into the oesophagus.
Moza contain Mosapride, a gastric prokinetic agent and serotonin (5HT) receptor agonist. Mosapride in Moza is a specific agonist of 5HT4 receptor, which is found in the stomach, and it does not have any action on the dopamine or acetylcholine receptors1. Stimulation of the 5HT4 receptor increases release of acetylcholine by the nerves supplying the stomach and this acts directly on the stomach muscle to increase peristalsis or natural waves of contraction that moves food towards the intestine. This prokinetic action of mosapride in Moza stimulates gastrointestinal motility and speeds up gastric emptying, as well as relieving pressure on the esophageal sphincter (muscle at the junction of the oesophagus and stomach), which in turn helps prevent reflux into the oesophagus.
The most commonly reported side effects when taking Moza include: diarrhoea, dry mouth, headache, nausea, insomnia, abdominal pain, dizziness.
You should not use Moza if you: are allergic to mosapride or any ingredients in Moza; are pregnant or are breastfeeding; have kidney or liver disease or respiratory failure; are taking medications that may prolong the QT-interval, including the antimalarial quinine, the antihistamine terfenadine, some antiarrhythmic medicines, such as amiodarone, quinidine, flecainide, sotalol, tricyclic antidepressants, such as amitriptyline, and some antipsychotic agents, such as phenothiazines, haloperidol, risperidone, as these increase risk of QT prolongation; are taking medications that may interact with Moza, including macrolide antibiotics, such as erythromycin, which increases the concentration of mosapride.
You should take your Moza with a glass of water 3 times daily, with or without food. The dose you take will depend on the condition you are being treated for and your doctor’s recommendation. You should continue to take your Moza for as long as recommended by your doctor, but nor for longer than 2 weeks. You should continue to take your Moza for as long as recommended by your doctor. Continuous administration of Moza is not recommended if no improvement in GI symptoms is observed after 2 weeks use.
If you miss a dose of Moza take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.
You should store your Moza below 25°C in a cool dry place.
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